Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1)

Mutations in the ligand-binding domain of the thyroid hormone receptor β (TRβ) lead to resistance to thyroid hormone (RTH). These TRβ mutants function in a dominant-negative fashion to interfere with the transcription activity of wild-type thyroid hormone receptors (TRs), leading to dysregulation of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fozzatti, Laura, Lu, Changxue, Kim, Dong Wook, Park, Jeong Won, Astapova, Inna, Gavrilova, Oksana, Willingham, Mark C., Hollenberg, Anthony N., Cheng, Sheue-yann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198316/
https://ncbi.nlm.nih.gov/pubmed/21987803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107474108
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados