The Nuclear Receptor Corepressor (NCoR) Controls Thyroid Hormone Sensitivity and the Set Point of the Hypothalamic-Pituitary-Thyroid Axis

The role of nuclear receptor corepressor (NCoR) in thyroid hormone (TH) action has been difficult to discern because global deletion of NCoR is embryonic lethal. To circumvent this, we developed mice that globally express a modified NCoR protein (NCoRΔID) that cannot be recruited to the thyroid horm...

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Detalhes bibliográficos
Main Authors: Astapova, Inna, Vella, Kristen R., Ramadoss, Preeti, Holtz, Kaila A., Rodwin, Benjamin A., Liao, Xiao-Hui, Weiss, Roy E., Rosenberg, Michael A., Rosenzweig, Anthony, Hollenberg, Anthony N.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386544/
https://ncbi.nlm.nih.gov/pubmed/21239618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0462
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