The Nuclear Receptor Corepressor (NCoR) Controls Thyroid Hormone Sensitivity and the Set Point of the Hypothalamic-Pituitary-Thyroid Axis

The role of nuclear receptor corepressor (NCoR) in thyroid hormone (TH) action has been difficult to discern because global deletion of NCoR is embryonic lethal. To circumvent this, we developed mice that globally express a modified NCoR protein (NCoRΔID) that cannot be recruited to the thyroid horm...

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Autori principali: Astapova, Inna, Vella, Kristen R., Ramadoss, Preeti, Holtz, Kaila A., Rodwin, Benjamin A., Liao, Xiao-Hui, Weiss, Roy E., Rosenberg, Michael A., Rosenzweig, Anthony, Hollenberg, Anthony N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386544/
https://ncbi.nlm.nih.gov/pubmed/21239618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0462
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