Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.

Loss of heterozygosity (LOH) at specific loci may help localize tumor suppressor genes involved in the formation of various familial and sporadic tumors. In addition, the genetic loci for a number of familial tumor syndromes have been mapped by linkage analysis. To explore the possible role of tumor...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Khosla, S, Patel, V M, Hay, I D, Schaid, D J, Grant, C S, van Heerden, J A, Thibodeau, S N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115186
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