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Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.

Loss of heterozygosity (LOH) at specific loci may help localize tumor suppressor genes involved in the formation of various familial and sporadic tumors. In addition, the genetic loci for a number of familial tumor syndromes have been mapped by linkage analysis. To explore the possible role of tumor...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Khosla, S, Patel, V M, Hay, I D, Schaid, D J, Grant, C S, van Heerden, J A, Thibodeau, S N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1991
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Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295269/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115186
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