Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.

Loss of heterozygosity (LOH) at specific loci may help localize tumor suppressor genes involved in the formation of various familial and sporadic tumors. In addition, the genetic loci for a number of familial tumor syndromes have been mapped by linkage analysis. To explore the possible role of tumor...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Khosla, S, Patel, V M, Hay, I D, Schaid, D J, Grant, C S, van Heerden, J A, Thibodeau, S N
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295269/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022740/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115186
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