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Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas.

Loss of heterozygosity (LOH) at specific loci may help localize tumor suppressor genes involved in the formation of various familial and sporadic tumors. In addition, the genetic loci for a number of familial tumor syndromes have been mapped by linkage analysis. To explore the possible role of tumor...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Khosla, S, Patel, V M, Hay, I D, Schaid, D J, Grant, C S, van Heerden, J A, Thibodeau, S N
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1991
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295269/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022740/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115186
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