Analysis of loss of heterozygosity of the tumor suppressor genes p53 and BRCA1 in ovarial carcinomas

Background/aim: Among the genes involved in ovarian carcinogenesis, there has been increased interest in tumor-suppressor genes p53 and BRCA1. Both of the genes make control of cell cycle, DNA repair and apoptosis. The p53 is a "genome guardian" inactivated in more than 50% of human cancers, while B...

Descrición completa

Detalles Bibliográficos

Principais autores:	Luković Ljiljana, Popović Branka, Atanacković Jasmina, Novaković Ivana, Perović Milica, Petrović Bojana, Petković Spasoje
Formato:	Artigo
Idioma:	Inglês
Publicado:	Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2006-01-01
Series:	Vojnosanitetski Pregled
Assuntos:	ovarian neoplasms loss of heterozygosity genes p53 BRCA1
Acceso en liña:	http://www.doiserbia.nb.rs/img/doi/0042-8450/2006/0042-84500609813P.pdf
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!