Analysis of loss of heterozygosity of the tumor suppressor genes p53 and BRCA1 in ovarial carcinomas

Background/aim: Among the genes involved in ovarian carcinogenesis, there has been increased interest in tumor-suppressor genes p53 and BRCA1. Both of the genes make control of cell cycle, DNA repair and apoptosis. The p53 is a "genome guardian" inactivated in more than 50% of human cancers, while B...

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Главные авторы:	Luković Ljiljana, Popović Branka, Atanacković Jasmina, Novaković Ivana, Perović Milica, Petrović Bojana, Petković Spasoje
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2006-01-01
Серии:	Vojnosanitetski Pregled
Предметы:	ovarian neoplasms loss of heterozygosity genes p53 BRCA1
Online-ссылка:	http://www.doiserbia.nb.rs/img/doi/0042-8450/2006/0042-84500609813P.pdf
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