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In Vitro Reconstitution of the Selection, Ubiquitination, and Membrane Extraction of a Polytopic ERAD Substrate

Secretory and membrane proteins that are destined for intracellular organelles in eukaryotes are first synthesized at the endoplasmic reticulum (ER) and are then delivered to their final destinations. The ER contains high concentrations of molecular chaperones and folding enzymes that assist substra...

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Autors principals: Nakatsukasa, Kunio, Brodsky, Jeffrey L.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950970/
https://ncbi.nlm.nih.gov/pubmed/20419421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-412-8_21
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