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In Vitro Reconstitution of the Selection, Ubiquitination, and Membrane Extraction of a Polytopic ERAD Substrate

Secretory and membrane proteins that are destined for intracellular organelles in eukaryotes are first synthesized at the endoplasmic reticulum (ER) and are then delivered to their final destinations. The ER contains high concentrations of molecular chaperones and folding enzymes that assist substra...

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Hlavní autoři: Nakatsukasa, Kunio, Brodsky, Jeffrey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950970/
https://ncbi.nlm.nih.gov/pubmed/20419421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-412-8_21
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