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Dissecting the ER-associated degradation of a misfolded polytopic membrane protein
It remains unclear how misfolded membrane proteins are selected and destroyed during endoplasmic reticulum associated degradation (ERAD). For example, chaperones are thought to solubilize aggregation-prone motifs, and some data suggest that these proteins are degraded at the ER. To better define how...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2219389/ https://ncbi.nlm.nih.gov/pubmed/18191224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.11.023 |
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