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Recent technical developments in the study of ER-associated degradation

Endoplasmic reticulum-associated degradation (ERAD) is a mechanism during which native and misfolded proteins are recognized and retrotranslocated across the ER membrane to the cytosol for degradation by the ubiquitin-proteasome system. Like other cellular pathways, the factors required for ERAD hav...

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Bibliographic Details
Main Authors: Nakatsukasa, Kunio, Kamura, Takumi, Brodsky, Jeffrey L.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130770/
https://ncbi.nlm.nih.gov/pubmed/24867671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2014.04.008
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