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Recent technical developments in the study of ER-associated degradation
Endoplasmic reticulum-associated degradation (ERAD) is a mechanism during which native and misfolded proteins are recognized and retrotranslocated across the ER membrane to the cytosol for degradation by the ubiquitin-proteasome system. Like other cellular pathways, the factors required for ERAD hav...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4130770/ https://ncbi.nlm.nih.gov/pubmed/24867671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2014.04.008 |
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