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The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum
Secretory and membrane proteins that fail to fold in the endoplasmic reticulum (ER) are retained and may be sorted for ER-associated degradation (ERAD). During ERAD, ER-associated components such as molecular chaperones and lectins recognize folding intermediates and specific oligosaccharyl modifica...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2754126/ https://ncbi.nlm.nih.gov/pubmed/18315532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2008.00729.x |
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