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The Recognition and Retrotranslocation of Misfolded Proteins from the Endoplasmic Reticulum

Secretory and membrane proteins that fail to fold in the endoplasmic reticulum (ER) are retained and may be sorted for ER-associated degradation (ERAD). During ERAD, ER-associated components such as molecular chaperones and lectins recognize folding intermediates and specific oligosaccharyl modifica...

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Detalles Bibliográficos
Main Authors: Nakatsukasa, Kunio, Brodsky, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754126/
https://ncbi.nlm.nih.gov/pubmed/18315532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2008.00729.x
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