Regulation of Tau Pathology by the Microglial Fractalkine Receptor

Aggregates of the hyperphosphorylated microtubule associated protein tau (MAPT) are an invariant neuropathological feature of tauopathies. Here we show that microglial neuroinflammation promotes MAPT phosphorylation and aggregation. First, lipopolysaccharide-induced microglial activation promotes hy...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bhaskar, Kiran, Konerth, Megan, Kokiko-Cochran, Olga N., Cardona, Astrid, Ransohoff, Richard M., Lamb, Bruce T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950825/
https://ncbi.nlm.nih.gov/pubmed/20920788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.08.023
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