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Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers with Cancer Risk and Mortality

CONTEXT: Risk-reducing mastectomy (RRM) and salpingo-oophorectomy (RRSO) are widely used by carriers of BRCA1 or BRCA2 mutations to reduce their risks of breast and ovarian cancer. OBJECTIVES: To estimate risk and mortality reduction stratified by mutation and prior cancer status. DESIGN: A prospect...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Domchek, Susan M., Friebel, Tara M., Singer, Christian F., Evans, D. Gareth, Lynch, Henry T., Isaacs, Claudine, Garber, Judy E., Neuhausen, Susan L., Matloff, Ellen, Eeles, Rosalind, Pichert, Gabriella, Van t'veer, Laura, Tung, Nadine, Weitzel, Jeffrey N., Couch, Fergus J., Rubinstein, Wendy S., Ganz, Patricia A., Daly, Mary B., Olopade, Olufunmilayo I., Tomlinson, Gail, Schildkraut, Joellen, Blum, Joanne L., Rebbeck, Timothy R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948529/
https://ncbi.nlm.nih.gov/pubmed/20810374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2010.1237
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