Use of Risk-Reducing Surgeries in a Prospective Cohort of 1,499 BRCA1 and BRCA2 Mutation Carriers

PURPOSE: Inherited mutations in BRCA1 or BRCA2 (BRCA1/2) confer very high risk of breast and ovarian cancers. Genetic testing and counseling can reduce risk and death from these cancers if appropriate preventive strategies are applied, including risk-reducing salpingo-oophorectomy (RRSO) or risk-red...

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Bibliografiset tiedot
Julkaisussa:Breast Cancer Res Treat
Päätekijät: Chai, Xinglei, Friebel, Tara M., Singer, Christian F., Evans, D. Gareth, Lynch, Henry T., Isaacs, Claudine, Garber, Judy E., Neuhausen, Susan L., Matloff, Ellen, Eeles, Rosalind, Tung, Nadine, Weitzel, Jeffrey N., Couch, Fergus J., Hulick, Peter J., Ganz, Patricia A., Daly, Mary B., Olopade, Olufunmilayo I., Tomlinson, Gail, Blum, Joanne L., Domchek, Susan M., Chen, Jinbo, Rebecck, Timothy R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224991/
https://ncbi.nlm.nih.gov/pubmed/25311111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3134-0
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