Use of Risk-Reducing Surgeries in a Prospective Cohort of 1,499 BRCA1 and BRCA2 Mutation Carriers

PURPOSE: Inherited mutations in BRCA1 or BRCA2 (BRCA1/2) confer very high risk of breast and ovarian cancers. Genetic testing and counseling can reduce risk and death from these cancers if appropriate preventive strategies are applied, including risk-reducing salpingo-oophorectomy (RRSO) or risk-red...

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Publicado no:Breast Cancer Res Treat
Main Authors: Chai, Xinglei, Friebel, Tara M., Singer, Christian F., Evans, D. Gareth, Lynch, Henry T., Isaacs, Claudine, Garber, Judy E., Neuhausen, Susan L., Matloff, Ellen, Eeles, Rosalind, Tung, Nadine, Weitzel, Jeffrey N., Couch, Fergus J., Hulick, Peter J., Ganz, Patricia A., Daly, Mary B., Olopade, Olufunmilayo I., Tomlinson, Gail, Blum, Joanne L., Domchek, Susan M., Chen, Jinbo, Rebecck, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224991/
https://ncbi.nlm.nih.gov/pubmed/25311111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-014-3134-0
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