Genetic Variation in IGF2 and HTRA1 and Breast Cancer Risk among BRCA1 and BRCA2 Carriers

BACKGROUND: BRCA1 and BRCA2 mutation carriers have a lifetime breast cancer risk of 40% to 80%, suggesting the presence of risk modifiers. We previously identified significant associations in genetic variants in the insulin-like growth factor (IGF) signaling pathway. Here, we investigate additional...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Neuhausen, Susan L., Brummel, Sean, Ding, Yuan Chun, Steele, Linda, Nathanson, Katherine L., Domchek, Susan, Rebbeck, Timothy R., Singer, Christian F., Pfeiler, Georg, Lynch, Henry T., Garber, Judy E., Couch, Fergus, Weitzel, Jeffrey N., Godwin, Andrew, Narod, Steven A., Ganz, Patricia A., Daly, Mary B., Isaacs, Claudine, Olopade, Olufunmilayo I., Tomlinson, Gail E., Rubinstein, Wendy S., Tung, Nadine, Blum, Joanne L., Gillen, Daniel L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352680/
https://ncbi.nlm.nih.gov/pubmed/21708937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-1336
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