Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers with Cancer Risk and Mortality

CONTEXT: Risk-reducing mastectomy (RRM) and salpingo-oophorectomy (RRSO) are widely used by carriers of BRCA1 or BRCA2 mutations to reduce their risks of breast and ovarian cancer. OBJECTIVES: To estimate risk and mortality reduction stratified by mutation and prior cancer status. DESIGN: A prospect...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Domchek, Susan M., Friebel, Tara M., Singer, Christian F., Evans, D. Gareth, Lynch, Henry T., Isaacs, Claudine, Garber, Judy E., Neuhausen, Susan L., Matloff, Ellen, Eeles, Rosalind, Pichert, Gabriella, Van t'veer, Laura, Tung, Nadine, Weitzel, Jeffrey N., Couch, Fergus J., Rubinstein, Wendy S., Ganz, Patricia A., Daly, Mary B., Olopade, Olufunmilayo I., Tomlinson, Gail, Schildkraut, Joellen, Blum, Joanne L., Rebbeck, Timothy R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948529/
https://ncbi.nlm.nih.gov/pubmed/20810374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2010.1237
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge