Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

Previously, we reported sipholenol A, a sipholane triterpenoid from the Red Sea sponge Callyspongia siphonella, as a potent reversal of multidrug resistance (MDR) in cancer cells that overexpressed P-glycoprotein (P-gp). Through extensive screening of several related sipholane triterpenoids that hav...

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Main Authors: Abraham, Ioana, Jain, Sandeep, Wu, Chung-Pu, Khanfar, Mohammad A., Kuang, Yehong, Dai, Chun-Ling, Shi, Zhi, Chen, Xiang, Fu, Liwu, Ambudkar, Suresh V., Sayed, Khalid El, Chen, Zhe-Sheng
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948058/
https://ncbi.nlm.nih.gov/pubmed/20696137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.08.001
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