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Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)

Fluorescent conjugates of drugs can be used to study cellular functions and pharmacology. These compounds interact with proteins as substrates or inhibitors, helping in the development of unique fluorescence-based methods to study in vivo localization and molecular mechanisms. P-glycoprotein (P-gp,...

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Библиографические подробности
Опубликовано в: :Drug Metab Dispos
Главные авторы: Sajid, Andaleeb, Raju, Natarajan, Lusvarghi, Sabrina, Vahedi, Shahrooz, Swenson, Rolf E., Ambudkar, Suresh V.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744393/
https://ncbi.nlm.nih.gov/pubmed/31371421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.087734
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