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Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1)

Fluorescent conjugates of drugs can be used to study cellular functions and pharmacology. These compounds interact with proteins as substrates or inhibitors, helping in the development of unique fluorescence-based methods to study in vivo localization and molecular mechanisms. P-glycoprotein (P-gp,...

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Bibliografische gegevens
Gepubliceerd in:Drug Metab Dispos
Hoofdauteurs: Sajid, Andaleeb, Raju, Natarajan, Lusvarghi, Sabrina, Vahedi, Shahrooz, Swenson, Rolf E., Ambudkar, Suresh V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744393/
https://ncbi.nlm.nih.gov/pubmed/31371421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.087734
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