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Identification of an Archaeal Presenilin-Like Intramembrane Protease
BACKGROUND: The GXGD-type diaspartyl intramembrane protease, presenilin, constitutes the catalytic core of the γ-secretase multi-protein complex responsible for activating critical signaling cascades during development and for the production of β-amyloid peptides (Aβ) implicated in Alzheimer's...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947513/ https://ncbi.nlm.nih.gov/pubmed/20927381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013072 |
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