Identification of an Archaeal Presenilin-Like Intramembrane Protease

BACKGROUND: The GXGD-type diaspartyl intramembrane protease, presenilin, constitutes the catalytic core of the γ-secretase multi-protein complex responsible for activating critical signaling cascades during development and for the production of β-amyloid peptides (Aβ) implicated in Alzheimer's...

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Bibliographische Detailangaben
Hauptverfasser: Torres-Arancivia, Celia, Ross, Carolyn M., Chavez, Jose, Assur, Zahra, Dolios, Georgia, Mancia, Filippo, Ubarretxena-Belandia, Iban
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947513/
https://ncbi.nlm.nih.gov/pubmed/20927381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013072
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