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Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis
Intramembrane-cleaving proteases (I-CLiPs) activate pools of single-pass helical membrane protein signaling precursors that are key in the physiology of prokaryotic and eukaryotic cells. Proteases typically cleave peptide bonds within extended or flexible regions of their substrates, and thus the me...
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| 出版年: | Biophys J |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954294/ https://ncbi.nlm.nih.gov/pubmed/29642028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.043 |
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