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Unwinding of the Substrate Transmembrane Helix in Intramembrane Proteolysis
Intramembrane-cleaving proteases (I-CLiPs) activate pools of single-pass helical membrane protein signaling precursors that are key in the physiology of prokaryotic and eukaryotic cells. Proteases typically cleave peptide bonds within extended or flexible regions of their substrates, and thus the me...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954294/ https://ncbi.nlm.nih.gov/pubmed/29642028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.01.043 |
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