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The Cα—H⋅⋅⋅O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions

The Cα—H⋅⋅⋅O hydrogen bond has been given little attention as a determinant of transmembrane helix association. Stimulated by recent calculations suggesting that such bonds can be much stronger than has been supposed, we have analyzed 11 known membrane protein structures and found that apparent carb...

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Bibliografiske detaljer
Main Authors: Senes, Alessandro, Ubarretxena-Belandia, Iban, Engelman, Donald M.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55372/
https://ncbi.nlm.nih.gov/pubmed/11481472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161280798
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