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The Cα—H⋅⋅⋅O hydrogen bond: A determinant of stability and specificity in transmembrane helix interactions

The Cα—H⋅⋅⋅O hydrogen bond has been given little attention as a determinant of transmembrane helix association. Stimulated by recent calculations suggesting that such bonds can be much stronger than has been supposed, we have analyzed 11 known membrane protein structures and found that apparent carb...

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Detalhes bibliográficos
Main Authors: Senes, Alessandro, Ubarretxena-Belandia, Iban, Engelman, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55372/
https://ncbi.nlm.nih.gov/pubmed/11481472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161280798
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