Loading...

Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector–triggered immune responses in vitro and in vivo

Adenovirus (Ad) vectors are widely used in human clinical trials. However, at higher dosages, Ad vector–triggered innate toxicities remain a major obstacle to many applications. Ad interactions with the complement system significantly contribute to innate immune responses in several models of Ad-med...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Seregin, Sergey S., Aldhamen, Yasser A., Appledorn, Daniel M., Hartman, Zachary C., Schuldt, Nathaniel J., Scott, Jeannine, Godbehere, Sarah, Jiang, Haixiang, Frank, Michael M., Amalfitano, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947391/
https://ncbi.nlm.nih.gov/pubmed/20511542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-276949
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!