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Novel Adenovirus Vectors ‘Capsid-Displaying’ a Human Complement Inhibitor

Adenovirus (Ad) vectors are currently the most commonly utilized gene transfer vectors in humans worldwide. Unfortunately, upon contact with the circulatory system, Ads induce several, innate, complement-dependent toxicities that limit the full potential for Ad-based gene transfer applications. Ther...

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Autors principals: Seregin, Sergey S., Hartman, Zachary C., Appledorn, Daniel M., Godbehere, Sarah, Jiang, Haixiang, Frank, Michael M., Amalfitano, Andrea
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895756/
https://ncbi.nlm.nih.gov/pubmed/20375551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000284368
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