β-Arrestins modulate Adenovirus vector induced innate immune responses: differential regulation by β-arrestin-1 and β-arrestin-2

Adenovirus (Ad) based vectors have been utilized in human gene transfer clinical trials since 1993. Unfortunately, innate immune responses directed against the Ad capsid and/or its genetic cargo can significantly limit the usage of Ad vectors. Previous studies have demonstrated that several signalin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Seregin, Sergey S., Appledorn, Daniel M., Patial, S., Bujold, M., Nance, W., Godbehere, S., Parameswaran, Narayanan, Amalfitano, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886295/
https://ncbi.nlm.nih.gov/pubmed/19896992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2009.10.023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados