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β-Arrestins modulate Adenovirus vector induced innate immune responses: differential regulation by β-arrestin-1 and β-arrestin-2
Adenovirus (Ad) based vectors have been utilized in human gene transfer clinical trials since 1993. Unfortunately, innate immune responses directed against the Ad capsid and/or its genetic cargo can significantly limit the usage of Ad vectors. Previous studies have demonstrated that several signalin...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
2009
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886295/ https://ncbi.nlm.nih.gov/pubmed/19896992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2009.10.023 |
| ট্যাগগুলো: |
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