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TRIF, and TRIF-Interacting TLRs Differentially Modulate Several Adenovirus Vector-Induced Immune Responses

The use of Adenovirus (Ad)-based vectors has proven to be a useful platform for the development of gene therapy and vaccine protocols. The immunological mechanisms underlying these properties need to be identified and understood to foster safer, more efficacious use of this important gene transfer p...

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Détails bibliographiques
Auteurs principaux: Appledorn, D.M., Patial, S., Godbehere, S., Parameswaran, N., Amalfitano, A.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853581/
https://ncbi.nlm.nih.gov/pubmed/20375595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000207194
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