Endogenous G(s)-Coupled Receptors in Smooth Muscle Exhibit Differential Susceptibility to GRK2/3-Mediated Desensitization

Although G protein-coupled receptor (GPCR) kinases (GRKs) have been shown to mediate desensitization of numerous GPCRs in studies using cellular expression systems, their function under physiological conditions is less well understood. In the current study, we employed various strategies to assess t...

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Detalhes bibliográficos
Main Authors: Kong, Kok Choi, Gandhi, Uma, Martin, T. J., Anz, Candace B., Yan, Huandong, Misior, Anna M., Pascual, Rodolfo M., Deshpande, Deepak A., Penn, Raymond B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947145/
https://ncbi.nlm.nih.gov/pubmed/18690720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801056w
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