β-Agonist-mediated Relaxation of Airway Smooth Muscle Is Protein Kinase A-dependent

Inhaled β-agonists are effective at reversing bronchoconstriction in asthma, but the mechanism by which they exert this effect is unclear and controversial. PKA is the historically accepted effector, although this assumption is made on the basis of associative and not direct evidence. Recent studies...

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Detalhes bibliográficos
Main Authors: Morgan, Sarah J., Deshpande, Deepak A., Tiegs, Brian C., Misior, Anna M., Yan, Huandong, Hershfeld, Alena V., Rich, Thomas C., Panettieri, Reynold A., An, Steven S., Penn, Raymond B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132805/
https://ncbi.nlm.nih.gov/pubmed/24973219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.557652
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