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A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle

A-kinase anchoring proteins (AKAPs) have emerged as important regulatory molecules that can compartmentalize cAMP signaling transduced by β2-adrenergic receptors (β(2)ARs); such compartmentalization ensures speed and fidelity of cAMP signaling and effects on cell function. This study aimed to assess...

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Hlavní autoři: Horvat, Sarah J., Deshpande, Deepak A., Yan, Huandong, Panettieri, Reynold A., Codina, Juan, DuBose, Thomas D., Xin, Wenkuan, Rich, Thomas C., Penn, Raymond B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425821/
https://ncbi.nlm.nih.gov/pubmed/22649031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-201020
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