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Compartmentalized cAMP responses to prostaglandin EP(2) receptor activation in human airway smooth muscle cells

BACKGROUND AND PURPOSE: Previous studies indicate that prostaglandin EP(2) receptors selectively couple to AC2 in non‐lipid raft domains of airway smooth muscle (ASM) cells, where they regulate specific cAMP‐dependent responses. The goal of the present study was to identify the cellular microdomains...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Agarwal, Shailesh R, Miyashiro, Kathryn, Latt, Htun, Ostrom, Rennolds S, Harvey, Robert D
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522994/
https://ncbi.nlm.nih.gov/pubmed/28603838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13904
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