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Effect of Adenylyl Cyclase Type 6 on Localized Production of cAMP by β-2 Adrenoceptors in Human Airway Smooth-Muscle Cells
β(2)-Adrenoceptors (β(2)ARs) are concentrated in caveolar lipid raft domains of the plasma membrane in airway smooth-muscle (ASM) cells, along with adenylyl cyclase type 6 (AC6). This is believed to contribute to how these receptors can selectively regulate certain types of cAMP-dependent responses...
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| Published in: | J Pharmacol Exp Ther |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6548981/ https://ncbi.nlm.nih.gov/pubmed/31068382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.256594 |
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