Anti-mitogenic effects of β-agonists and PGE(2) on airway smooth muscle are PKA dependent

Inhaled β-agonists are effective airway smooth muscle (ASM)-relaxing agents that help reverse bronchoconstriction in asthma, but their ability to affect the aberrant ASM growth that also occurs with asthma is poorly understood. β-Agonists exhibit PKA-dependent antimitogenic effects in several cell t...

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Hauptverfasser: Yan, Huandong, Deshpande, Deepak A., Misior, Anna M., Miles, Matthew C., Saxena, Himansh, Riemer, Ellen C., Pascual, Rodolfo M., Panettieri, Reynold A., Penn, Raymond B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2011
Schlagworte:
Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005432/
https://ncbi.nlm.nih.gov/pubmed/20805374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-164798
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