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Agonist-Promoted Homologous Desensitization of Human Airway Smooth Muscle Bitter Taste Receptors
Bitter taste receptors (TAS2Rs) were shown to be expressed in human airway smooth muscle (ASM). They couple to specialized [Ca(2+)](i) release, leading to membrane hyperpolarization, the relaxation of ASM, and marked bronchodilation. TAS2Rs are G-protein–coupled receptors, known to undergo rapid ago...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361362/ https://ncbi.nlm.nih.gov/pubmed/21642585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0061OC |
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