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Bitter taste receptor agonists alter mitochondrial function and induce autophagy in airway smooth muscle cells
Airway remodeling, including increased airway smooth muscle (ASM) mass, is a hallmark feature of asthma and COPD. We previously identified the expression of bitter taste receptors (TAS2Rs) on human ASM cells and demonstrated that known TAS2R agonists could promote ASM relaxation and bronchodilation...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5538869/ https://ncbi.nlm.nih.gov/pubmed/28450286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00106.2017 |
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