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‘Umpolung’ Reactivity in Semiaqueous Amide and Peptide Synthesis

The amide functional group is one of Nature’s key functional and structural elements, most notably within peptides. Amides are also key intermediates in the preparation of a diverse range of therapeutic small molecules. Its construction using available methods focuses principally upon dehydrative ap...

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Détails bibliographiques
Auteurs principaux: Shen, Bo, Makley, Dawn M., Johnston, Jeffrey N.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945247/
https://ncbi.nlm.nih.gov/pubmed/20577205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09125
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