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The inverted ketene synthon: a double umpolung approach to enantioselective β(2,3)-amino amide synthesis
A stereocontrolled synthesis of β(2,3)-amino amides is reported. Innovation is encapsulated by the first use of nitroalkenes to achieve double umpolung in enantioselective β-amino amide synthesis. Step economy is also fulfilled by the use of Umpolung Amide Synthesis (UmAS) in the second step, delive...
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| Publicado no: | Chem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6349014/ https://ncbi.nlm.nih.gov/pubmed/30774911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04330b |
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