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Enantioselective synthesis of d-α-amino amides from aliphatic aldehydes

Peptides consisting of d-amino amides are highly represented among both biologically active natural products and non-natural small molecules used in therapeutic development. Chemical synthesis of d-amino amides most often involves approaches based on enzymatic resolution or fractional recrystallizat...

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Publicat a:Chem Sci
Autors principals: Schwieter, Kenneth E., Johnston, Jeffrey N.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378585/
https://ncbi.nlm.nih.gov/pubmed/25838883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc00064e
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