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‘Umpolung’ Reactivity in Semiaqueous Amide and Peptide Synthesis
The amide functional group is one of Nature’s key functional and structural elements, most notably within peptides. Amides are also key intermediates in the preparation of a diverse range of therapeutic small molecules. Its construction using available methods focuses principally upon dehydrative ap...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945247/ https://ncbi.nlm.nih.gov/pubmed/20577205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09125 |
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