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Nucleostemin: Another nucleolar “Twister” of the p53-MDM2 loop

Several nucleolar proteins, such as ARF, ribosomal protein (RP) L5, L11, L23 and S7, have been shown to induce p53 activation by inhibiting MDM2 E3 ligase activity and consequently to trigger cell cycle arrest and/or apoptosis. Our recent study revealed another nucleolar protein called nucleostemin...

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Bibliografske podrobnosti
Main Authors: Lo, Dorothy, Lu, Hua
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943035/
https://ncbi.nlm.nih.gov/pubmed/20703089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.16.12605
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