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Nucleostemin: Another nucleolar “Twister” of the p53-MDM2 loop

Several nucleolar proteins, such as ARF, ribosomal protein (RP) L5, L11, L23 and S7, have been shown to induce p53 activation by inhibiting MDM2 E3 ligase activity and consequently to trigger cell cycle arrest and/or apoptosis. Our recent study revealed another nucleolar protein called nucleostemin...

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Bibliografiske detaljer
Main Authors: Lo, Dorothy, Lu, Hua
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943035/
https://ncbi.nlm.nih.gov/pubmed/20703089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.16.12605
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