Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress

Nucleolar proteins play an important role in the regulation of the MDM2–p53 pathway, which coordinates cellular response to stress. However, the mechanism underlying this regulation remains poorly understood. Here, we report that the nucleolar protein CSIG is a novel and crucial regulator of the MDM...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Xie, Nan, Ma, Liwei, Zhu, Feng, Zhao, Wenhui, Tian, Feng, Yuan, Fuwen, Fu, Jingxuan, Huang, Daoyuan, Lv, Cuicui, Tong, Tanjun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095888/
https://ncbi.nlm.nih.gov/pubmed/27811966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36171
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