Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress

Nucleolar proteins play an important role in the regulation of the MDM2–p53 pathway, which coordinates cellular response to stress. However, the mechanism underlying this regulation remains poorly understood. Here, we report that the nucleolar protein CSIG is a novel and crucial regulator of the MDM...

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Publicat a:Sci Rep
Autors principals: Xie, Nan, Ma, Liwei, Zhu, Feng, Zhao, Wenhui, Tian, Feng, Yuan, Fuwen, Fu, Jingxuan, Huang, Daoyuan, Lv, Cuicui, Tong, Tanjun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095888/
https://ncbi.nlm.nih.gov/pubmed/27811966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36171
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