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Nucleolar TRF2 attenuated nucleolus stress-induced HCC cell-cycle arrest by altering rRNA synthesis

The nucleolus is an important organelle that is responsible for the biogenesis of ribosome RNA (rRNA) and ribosomal subunits assembly. It is also deemed to be the center of metabolic control, considering the critical role of ribosomes in protein translation. Perturbations of rRNA synthesis are close...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yuan, Fuwen, Xu, Chenzhong, Li, Guodong, Tong, Tanjun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938709/
https://ncbi.nlm.nih.gov/pubmed/29725012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0572-3
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