Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus

Nucleoli have attracted interest for their role as cellular stress sensors and as potential targets for cancer treatment. The effect of DNA double-strand breaks (DSBs) in nucleoli on rRNA transcription and nucleolar organisation appears to depend on the agent used to introduce DSBs, DSB frequency an...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Siebenwirth, Christian, Greubel, Christoph, Drexler, Guido A., Reindl, Judith, Walsh, Dietrich W. M., Schwarz, Benjamin, Sammer, Matthias, Baur, Iris, Pospiech, Helmut, Schmid, Thomas E., Dollinger, Günther, Friedl, Anna A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803363/
https://ncbi.nlm.nih.gov/pubmed/31492757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232181
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