Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus

Nucleoli have attracted interest for their role as cellular stress sensors and as potential targets for cancer treatment. The effect of DNA double-strand breaks (DSBs) in nucleoli on rRNA transcription and nucleolar organisation appears to depend on the agent used to introduce DSBs, DSB frequency an...

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Detalles Bibliográficos
Publicado en:J Cell Sci
Main Authors: Siebenwirth, Christian, Greubel, Christoph, Drexler, Guido A., Reindl, Judith, Walsh, Dietrich W. M., Schwarz, Benjamin, Sammer, Matthias, Baur, Iris, Pospiech, Helmut, Schmid, Thomas E., Dollinger, Günther, Friedl, Anna A.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803363/
https://ncbi.nlm.nih.gov/pubmed/31492757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232181
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