Local inhibition of rRNA transcription without nucleolar segregation after targeted ion irradiation of the nucleolus

Nucleoli have attracted interest for their role as cellular stress sensors and as potential targets for cancer treatment. The effect of DNA double-strand breaks (DSBs) in nucleoli on rRNA transcription and nucleolar organisation appears to depend on the agent used to introduce DSBs, DSB frequency an...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Siebenwirth, Christian, Greubel, Christoph, Drexler, Guido A., Reindl, Judith, Walsh, Dietrich W. M., Schwarz, Benjamin, Sammer, Matthias, Baur, Iris, Pospiech, Helmut, Schmid, Thomas E., Dollinger, Günther, Friedl, Anna A.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803363/
https://ncbi.nlm.nih.gov/pubmed/31492757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.232181
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