Chromatin organization revealed by nanostructure of irradiation induced γH2AX, 53BP1 and Rad51 foci

The spatial distribution of DSB repair factors γH2AX, 53BP1 and Rad51 in ionizing radiation induced foci (IRIF) in HeLa cells using super resolution STED nanoscopy after low and high linear energy transfer (LET) irradiation was investigated. 53BP1 and γH2AX form IRIF with same mean size of (540 ± 40...

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發表在:Sci Rep
Main Authors: Reindl, Judith, Girst, Stefanie, Walsh, Dietrich W. M., Greubel, Christoph, Schwarz, Benjamin, Siebenwirth, Christian, Drexler, Guido A., Friedl, Anna A., Dollinger, Günther
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240115/
https://ncbi.nlm.nih.gov/pubmed/28094292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40616
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